https://pharmatlas.org/ 2026-04-06T07:37:03+00:00 https://pharmatlas.org/ https://pharmatlas.org/lib/exe/fetch.php?media=logo.png text/html 2026-02-13T01:13:42+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:amlodipine&rev=1770945222&do=diff Amlodipine Amlodipine is a long-acting Dihydropyridine Calcium Channel Blocker (DHP CCB). It primarily causes arterial vasodilation and reduces systemic vascular resistance. Used in: * Hypertension * Stable Angina * Vasospastic angina → Calcium Channel Blockers ---------- Mechanism of Action Amlodipine blocks L-type calcium channels in vascular smooth muscle. text/html 2026-02-13T01:18:49+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:clevidipine&rev=1770945529&do=diff Clevidipine Clevidipine is an ultra–short-acting Dihydropyridine Calcium Channel Blocker (DHP CCB). It is a potent, rapidly titratable intravenous arterial vasodilator used in hypertensive emergencies. Used in: * Hypertensive emergency * Perioperative blood pressure control * Neurocritical care BP management text/html 2026-02-13T01:16:08+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:dhp&rev=1770945368&do=diff Dihydropyridine Calcium Channel Blockers Dihydropyridine Calcium Channel Blockers (DHP CCBs) are potent arterial vasodilators that reduce systemic vascular resistance (SVR) by blocking L-type calcium channels in vascular smooth muscle. They are primarily used for: text/html 2026-02-13T01:14:51+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:diltiazem&rev=1770945291&do=diff Diltiazem Diltiazem is a Non-Dihydropyridine Calcium Channel Blocker (Non-DHP CCB). It has both cardiac and vascular effects and is commonly used for rate control and angina. Used in: * Dysrhythmias * Stable Angina * Hypertension → Calcium Channel Blockers ---------- Mechanism of Action Diltiazem blocks L-type calcium channels in: * SA node text/html 2026-02-13T01:17:33+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:felodipine&rev=1770945453&do=diff Felodipine Felodipine is a Dihydropyridine Calcium Channel Blocker (DHP CCB). It primarily causes arterial vasodilation and reduces systemic vascular resistance. Used in: * Hypertension * Stable Angina → Calcium Channel Blockers ---------- Mechanism of Action Felodipine blocks L-type calcium channels in vascular smooth muscle. text/html 2026-02-13T01:18:12+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:nicardipine&rev=1770945492&do=diff Nicardipine Nicardipine is a Dihydropyridine Calcium Channel Blocker (DHP CCB). It is a potent arterial vasodilator available in both oral and intravenous formulations. Used in: * Hypertension * Hypertensive emergency (IV) * Angina → Calcium Channel Blockers ---------- Mechanism of Action Nicardipine blocks L-type calcium channels in vascular smooth muscle. text/html 2026-02-13T01:17:01+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:nifedipine&rev=1770945421&do=diff Nifedipine Nifedipine is a Dihydropyridine Calcium Channel Blocker (DHP CCB). It primarily causes arterial vasodilation and reduces systemic vascular resistance. Used in: * Hypertension * Stable Angina * Vasospastic angina * Raynaud phenomenon → Calcium Channel Blockers ---------- Mechanism of Action Nifedipine blocks L-type calcium channels in vascular smooth muscle. text/html 2026-02-12T23:23:52+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:non_dhp&rev=1770938632&do=diff Non-Dihydropyridine Calcium Channel Blockers Non-Dihydropyridine Calcium Channel Blockers (Non-DHP CCBs) block L-type calcium channels in both cardiac myocytes and vascular smooth muscle. Unlike Dihydropyridine Calcium Channel Blockers, Non-DHP agents significantly affect cardiac conduction and contractility. text/html 2026-02-13T01:13:10+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:start&rev=1770945190&do=diff Calcium Channel Blockers (CCBs) Calcium Channel Blockers inhibit L-type calcium channels in cardiac and vascular smooth muscle. They reduce intracellular calcium, leading to: * ↓ Contractility * ↓ Heart rate (some agents) * ↓ Afterload text/html 2026-02-13T01:14:14+00:00 Anonymous (anonymous@undisclosed.example.com) https://pharmatlas.org/doku.php?id=cardio:ccb:verapamil&rev=1770945254&do=diff Verapamil Verapamil is a Non-Dihydropyridine Calcium Channel Blocker (Non-DHP CCB). It primarily affects cardiac tissue and AV nodal conduction. Used in: * Dysrhythmias (rate control) * Stable Angina * Hypertension → Calcium Channel Blockers ---------- Mechanism of Action Verapamil blocks L-type calcium channels in: * SA node * AV node