====== Immunosuppressants ======Organized by mechanism, target, and clinical use
This section covers systemic immunosuppressive therapies across specialties(rheumatology, transplant, dermatology, GI, nephrology, neurology).
—-===== Core Classes ========= Conventional / Antimetabolites ==== * Methotrexate * Azathioprine * Mycophenolate * Leflunomide==== Calcineurin / mTOR ==== * Tacrolimus * Cyclosporine * Sirolimus / Everolimus==== Biologic Agents ==== * TNF inhibitors * IL‑6 inhibitors * IL‑17 inhibitors * IL‑12/23 inhibitors * B‑cell depletion * T‑cell co‑stimulation * Complement inhibitors==== Targeted Small Molecules ==== * JAK inhibitors * PDE4 inhibitors * S1P receptor modulators==== Glucocorticoids ==== * Systemic steroids—-===== Cross‑Cutting Topics ===== * Monitoring & lab surveillance * Infection risk & vaccines * TB / Hep B screening * Pregnancy & lactation * Drug interactions * Malignancy risk—-===== Disease / Indication Index ===== * Transplant immunosuppression * Inflammatory Bowel Disease * Dermatologic indications * Neuro‑immunology * Nephrology / GN