endocrine:adrenal:start
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Adrenal
The adrenal axis includes:
- Glucocorticoids (cortisol)
- Mineralocorticoids (aldosterone)
- Adrenal androgens
- Steroid synthesis pathways
- ACTH regulation
Glucocorticoids
[[endocrine:glucocorticoids:start|Glucocorticoids]]
Short-Acting:
- Hydrocortisone (Cortef®)
Intermediate-Acting:
- Prednisone (Deltasone®)
- Methylprednisolone (Medrol®)
Long-Acting:
- Dexamethasone (Decadron®)
Used in:
- Adrenal insufficiency
- Inflammatory disorders
- Autoimmune disease
- Cerebral edema
- Oncology
Mineralocorticoids
[[endocrine:mineralocorticoids:start|Mineralocorticoids]]
- Fludrocortisone (Florinef®)
Used in:
- Primary adrenal insufficiency
- Salt-wasting congenital adrenal hyperplasia
Steroid Synthesis Inhibitors
[[endocrine:adrenal:steroid_synthesis_inhibitors|Steroid Synthesis Inhibitors]]
- Osilodrostat (Isturisa®)
- Etomidate (IV for severe Cushing’s)
- Abiraterone (Zytiga®)
Used in:
- Cushing syndrome
- Hypercortisolism
- Prostate cancer (abiraterone)
Glucocorticoid Receptor Antagonists
Aldosterone Antagonists
(Linked in Cardiovascular but physiologically adrenal)
- Spironolactone (Aldactone®)
- Eplerenone (Inspra®)
Used in:
- Primary hyperaldosteronism
- Resistant hypertension
- Heart failure
ACTH & Diagnostic Agents
Adrenolytic Agents
Pheochromocytoma & Catecholamine Excess
Clinical Groupings
Adrenal Insufficiency:
- Hydrocortisone
- Fludrocortisone
Cushing Syndrome:
- Ketoconazole
- Metyrapone
- Osilodrostat
- Mifepristone
- Mitotane
Primary Hyperaldosteronism:
- Spironolactone
- Eplerenone
Adrenocortical Carcinoma:
- Mitotane
endocrine/adrenal/start.1770991991.txt.gz · Last modified: by andrew2393cns