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office_hours:series:start [2026/02/15 17:38] – [Pain Physiology & Mechanisms] andrew2393cnsoffice_hours:series:start [2026/02/16 02:01] (current) – andrew2393cns
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-Office Hours: Series is where pharmacology is reconciled.+== **Office Hours: Series** == is where pharmacology is reconciled.
  
 These sessions step back from individual drugs and focus on: These sessions step back from individual drugs and focus on:
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   * How scattered topics connect into one framework   * How scattered topics connect into one framework
  
-This is not memorization.+----
  
-This is integration. +{{:office_hours:series:pain.png?350|}}
- +
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- +
-{{:office_hours:series:pain.png?300|}}+
 ==== Pain Physiology & Mechanisms ==== ==== Pain Physiology & Mechanisms ====
  
-Understanding pain requires moving through: +  * Pain is a signal — but it is also an experience. 
- +  * This series breaks pain into its components: nociception, transmission, modulation, and central amplification. We will differentiate acute inflammatory pain from neuropathic pain and centralized pain, and explain why each responds differently to medications. 
-  * Peripheral transduction +  * Instead of asking “what drug do I give?”, you’ll start asking “where in the pathway is the dysfunction?”
-  * Nerve transmission +
-  * Spinal modulation +
-  * Central perception+
  
 → [[office_hours:pain:start|Enter Pain Series]] → [[office_hours:pain:start|Enter Pain Series]]
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 This series connects: This series connects:
  
-  * Cytokines and signaling pathways +  * Inflammation is the body’s protective response — until it isn’t. 
-  * Acute vs chronic inflammation +  * This series maps the immune cascade from tissue injury to cytokine signaling. You’ll see how histamine, prostaglandins, leukotrienes, and interleukins connect — and how medications intervene at different depths of the pathway. 
-  * Autoimmune vs allergic disease +  * Understanding the cascade allows you to predict both therapeutic effects and immunologic risk.
-  * Why NSAIDs, steroids, and biologics act differently+
  
 → [[office_hours:inflammation:start|Enter Inflammation Series]] → [[office_hours:inflammation:start|Enter Inflammation Series]]
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 ==== Migraines ==== ==== Migraines ====
  
-  * xxx +  * Migraine is not “just a bad headache.” 
-  * xxx +  * It is a neurologic disorder involving cortical excitability, trigeminovascular activation, and inflammatory neuropeptides like CGRP. This series explores how those pathways produce aura, photophobia, nausea, and pain — and how targeted therapies interrupt them. 
-  * xxx+  * You will move from symptom recognition to mechanism-driven treatment decisions.
  
 → [[office_hours:migraine:start|Migraine Series]] → [[office_hours:migraine:start|Migraine Series]]
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 ==== Obesity ==== ==== Obesity ====
  
-  * xxx +  * Obesity is not simply about excess weight — it is about dysregulated energy signaling. 
-  * xxx +  * This series examines how the brain, gut hormones, adipose tissue, insulin, and reward pathways interact to regulate body weight. We will unpack why long-term weight loss is biologically difficult, why set points matter, and how modern pharmacology changes the equation. 
-  * xxx+  * By the end, you will understand obesity as a chronic metabolic disease — not a lifestyle choice.
  
 → [[office_hours:obesity:start|Obesity Series]] → [[office_hours:obesity:start|Obesity Series]]
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-===== Format =====+{{:office_hours:series:vitmains.png?300|}} 
 +==== Vitamins and Minerals ====
  
-Each Series topic includes:+  * One of the most common questions you’ll hear in clinic is: “What vitamins should I take?” If you don’t understand what they actually do, you can’t give a meaningful answer. 
 +  * This series is designed to move beyond memorizing deficiency lists and instead understand how vitamins and minerals function at a biochemical and physiologic level. 
 +  * Most medical curricula barely scratch the surface of micronutrient physiology. This series fills that gap by building a clear framework — from mechanism to clinical application.
  
-  * Embedded video +→ [[office_hours:vitamins:start|Vitamins and Minerals Series]]
-  * Downloadable PDF +
-  * Visual pathway diagrams +
-  * Linked PharmAtlas drug references+
  
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- +
-===== Who This Is For ===== +
- +
-Office Hours: Series is ideal for: +
- +
-  * Students preparing for exams +
-  * Learners who feel topics are fragmented +
-  * Clinicians who want conceptual refreshers +
-  * Anyone who wants to understand mechanisms deeply +
- +
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- +
-===== Teaching Philosophy ===== +
- +
-If you understand the mechanism: +
- +
-You do not need to memorize the drug list. +
- +
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 Related: Related:
office_hours/series/start.1771177081.txt.gz · Last modified: by andrew2393cns