Differences

This shows you the differences between two versions of the page.

--- endocrine:drug_classes:corticosteroids [2026/02/12 20:16] – andrew2393cns
+++ endocrine:drug_classes:corticosteroids [2026/02/12 20:18] (current) – [Topical Dermatologic Glucocorticoids] andrew2393cns
@@ Line 11: / Line 11: @@
   * [[endocrine:physiology:glucocorticoid_signaling|Glucocorticoid Signaling Pathway]]
-----
+★ = High-yield / core drug for mastery
-===== ★ Core Drugs to Master (PA Board Focus) =====
-Systemic:
-  * [[endocrine:drugs:hydrocortisone|Hydrocortisone]]
-  * [[endocrine:drugs:prednisone|Prednisone]]
-  * [[endocrine:drugs:prednisolone|Prednisolone]]
-  * [[endocrine:drugs:methylprednisolone|Methylprednisolone]]
-  * [[endocrine:drugs:dexamethasone|Dexamethasone]]
-  * [[endocrine:drugs:betamethasone|Betamethasone]]
-Inhaled / Intranasal:
-  * [[endocrine:drugs:fluticasone|Fluticasone]]
-  * [[endocrine:drugs:budesonide|Budesonide]]
-Topical:
-  * [[endocrine:drugs:hydrocortisone|Hydrocortisone]]
-  * [[endocrine:drugs:triamcinolone|Triamcinolone]]
-  * [[endocrine:drugs:clobetasol|Clobetasol]]
-Mineralocorticoid:
-  * [[endocrine:drugs:fludrocortisone|Fludrocortisone]]
-(★ in tables below indicates high-yield focus drug.)
 ----
@@ Line 41: / Line 17: @@
 ===== Systemic Glucocorticoids =====
-^ Drug ^ Relative GC Potency ^ Mineralocorticoid Activity ^ Duration ^ Core ^
+^ Drug ^ Relative GC Potency ^ Mineralocorticoid Activity ^ Duration ^ ★ ^
 | [[endocrine:drugs:hydrocortisone|Hydrocortisone]] | Low | Moderate | Short | ★ |
 | [[endocrine:drugs:cortisone|Cortisone]] | Low | Moderate | Short |  |
@@ Line 50: / Line 26: @@
 | [[endocrine:drugs:dexamethasone|Dexamethasone]] | High | None | Long | ★ |
 | [[endocrine:drugs:betamethasone|Betamethasone]] | High | None | Long | ★ |
-Clinical integration:
-  * [[respiratory:clinical:asthma|Asthma]]
-  * [[rheumatology:clinical:rheumatoid_arthritis|Rheumatoid Arthritis]]
-  * [[gastroenterology:clinical:ibd|Inflammatory Bowel Disease]]
 ----
@@ Line 60: / Line 31: @@
 ===== Inhaled Glucocorticoids =====
-^ Drug ^ Notes ^ Core ^
+^ Drug ^ Notes ^ ★ ^
 | [[endocrine:drugs:beclomethasone|Beclomethasone]] | Early ICS |  |
 | [[endocrine:drugs:budesonide|Budesonide]] | Also GI-targeted form | ★ |
@@ Line 75: / Line 46: @@
 ===== Intranasal Glucocorticoids =====
-^ Drug ^ Notes ^ Core ^
+^ Drug ^ Notes ^ ★ ^
 | [[endocrine:drugs:beclomethasone|Beclomethasone]] | Also inhaled |  |
 | [[endocrine:drugs:budesonide|Budesonide]] | Also inhaled | ★ |
@@ Line 90: / Line 61: @@
 ===== Topical Dermatologic Glucocorticoids =====
-^ Drug ^ Typical Potency ^ Core ^
+^ Drug ^ Typical Potency ^ ★ ^
 | [[endocrine:drugs:hydrocortisone|Hydrocortisone]] | Low | ★ |
 | [[endocrine:drugs:desonide|Desonide]] | Low–Moderate |  |
 | [[endocrine:drugs:triamcinolone|Triamcinolone]] | Moderate | ★ |
-| [[endocrine:drugs:betamethasone|Betamethasone]] | High |  |
+| [[endocrine:drugs:betamethasone|Betamethasone]] | High | ★ |
 | [[endocrine:drugs:fluocinonide|Fluocinonide]] | High |  |
 | [[endocrine:drugs:clobetasol|Clobetasol]] | Very High | ★ |
@@ Line 106: / Line 77: @@
 ===== GI-Targeted Glucocorticoids =====
-^ Drug ^ Notes ^ Core ^
+^ Drug ^ Notes ^ ★ ^
 | [[endocrine:drugs:budesonide|Budesonide]] | High first-pass metabolism | ★ |
 | [[endocrine:drugs:hydrocortisone|Hydrocortisone]] | Rectal formulations |  |
@@ Line 117: / Line 88: @@
 ===== Mineralocorticoids =====
-^ Drug ^ Primary Use ^ Core ^
+^ Drug ^ Primary Use ^ ★ ^
 | [[endocrine:drugs:fludrocortisone|Fludrocortisone]] | Adrenal insufficiency | ★ |
@@ Line 145: / Line 116: @@
 ===== High-Yield Pearls =====
-  * Dexamethasone and betamethasone have **no mineralocorticoid activity**.
+  * Dexamethasone and betamethasone have no mineralocorticoid activity.
-  * Inhaled corticosteroids are foundational in asthma.
+  * Inhaled steroids are foundational therapy in asthma.
   * Intranasal steroids are first-line for allergic rhinitis congestion.
   * Chronic systemic use suppresses ACTH.
   * One molecule = one page; routes described within drug monographs.